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VALERIANATE AND HyDKOCYANATE OF ZlNC.
777
fW s a tonic and antispasmodic ; large doses occasion vomiting and purging.
, au x and Dejaer 1 deny that it is a poison, even in large doses.e^ ,'. Es -"—Tt is rare.ly administered internally; but is applicable as anS|,| , ° ! tonic, and antispasmodic, in the same cases in which the oxide or•ß of zinc is employed. As a topical remedy, it is used, on account ofgent qualities, in chronic Ophthalmia, gleet, and leucorrhoea. In the
! ts astri n
'att,
pLj. sta ges of gonorrhcea I have found it far more successful than the sul-{j e> Its beneficial effects were first described by the late Dr. WilliamMn 2' °^ Manchester. 2 Sir A. Cooper 3 recommmends, as the best injectionof I can be used in the third week of gonorrhcea, a mixture of six grains%t ^ e °^ Z " 1C anc ' f° ur ounces of liquor plumbi subacetatis dilutus. Ofa Ce j. e double decomposition takes place, and the active ingredient is the, ate of z j nc>
t] le i äIIN iSTRATiON.—When exhibited internally, as a tonic or antispasmodic,a( Jttii° Se ' s one or * wo S ra i ns gradually increased. As an emetic it is rarelySfif e '^ered : the dose is from ten grains to a scruple : its Operation is veryCojrt • • a l°tion or injection, it is employed in the form of aqueous SolutionDing two or more grains of the salt to an ounce of water.
\
122. Zinci Valerianas. — Valerianate of Zinc.
w- e -Dublin Pharmacopceia contains the subjoined formula for this pre-
3 f Valerianate of Soda, Jiiss.; Sulphate of Zinc, gij. and 5vii.; Distilled Water,
in one half, and tlie sulphate of zinc in the
>i
D:
%aj D ; lss olve the valerianate of sodas «itv, „£S half of the water: and havina
Kl!1) off S i Ilalt °*' * ne w& ter! an( l having raised both Solutions to 200°, mix them, andf^ituf e crystals which are produced. Let the Solution be now evaporated at a tem-pore j, 110 * exceediug 200°, until it is reduced to the bulk of four ounces, removing, as^ e crystals from the surface, in proportion as they form, and placing them with
* a 8 100°
-j ^u.-onicu The salt thus produced is to be steeped for an hour in as muche dun»' i e 5 w ater as is just sufficient to cover it, and then dried at a heat not ex-
l *3.
Zinci Cyanidum.
-Hydrocyanate, Cyanide, or Cyanuretof Zinc.
Formula ZnCy. äquivalent WeigM 58'5.
' 1 <M < Wag i n t ro duced, by the German physicians, as a Substitute for hydrocyanic1) 'ga ls 1 P r . e P arec 'by adding recently-made oxide of zinc to hydrocyanic acid; or byc der • u tion of sulphate of zinc to a Solution of Cyanide of potassium. It is a whiteJ'ftic L^^Me in water or alcohol. If a strong mineral acid be addcd to it, hydro-I) tcs ts h f S d ere l°P e| l, an d a s °lable salt of zinc obtained. The latter is recognised byr s °f ? •■ re mentioned for a Solution of zinc. It oonsists of one equivalent or 32tl s effe ? Cj and one e( l u ^ va ^ eni or 26 P ai 'ts of Ot/anogew.
J 0s o 0 { i C ™ have not been earefully asoertained, but they are supposed to be similar ton ' s 'e»i. 'y^rocyanic acid. It has been used principallv in affcctions of the nervous
s; t0a
nervouss 0 p j,°P'' e psy, hysteria, and Chorea. It has also been employed ir -
Wie stomach, and as an anthclmintic in childreu. The dose is a quarter of a
e d Wi grain an d a half three times a* ltu calcined
. magnesia.
It has also been employed in cardialgia andin childreu. The dose isIt may be taten in the form of powder
1 Orfila, Toxicol. Gen.
■ Lond. Med. and I'hys. Joum. ix. 53, 1803.
3 Lancet, iii. 199.